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Article

A microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with risk for melanoma.

International journal of cancer - 15 Sept 2006

Okamoto Ichiro, Krögler Julia, Endler Georg, Kaufmann Stefan, Mustafa Stefan, Exner Markus, Mannhalter Christine, Wagner Oswald, Pehamberger Hubert

Abstract excerpt

Heme oxygenase-1 (HO-1) has been demonstrated to play an important role in the regulation of signaling systems, which are involved in the control of cell cycle progression and apoptosis. Recently, a (GT)n dinucleotide repeat polymorphism in the HO-1 promoter was shown to modulate HO-1 gene expression. Short (<25 GT) repeats are associated with an increased HO-1 upregulation after stimulation than are longer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16596642
DOI: 10.1002/ijc.21937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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