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Article

Missense polymorphisms in matrix metalloproteinase genes and skin cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2008

Nan Hongmei, Niu Tianhua, Hunter David J, Han Jiali

Abstract excerpt

Matrix metalloproteinases (MMP) degrade various components of the extracellular matrix, and their overexpression has been implicated in tumor progression. Nonsynonymous single nucleotide polymorphisms (SNPs) lead to amino acid substitutions that can alter the function of the encoded protein. We evaluated the associations of six nonsynonymous SNPs in the MMP3, MMP8, and MMP9 genes with skin cancer risk in a nested...

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Source

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Identifiers

PMID: 19064570
DOI: 10.1158/1055-9965.EPI-08-0606
PMCID: PMC2664625

Genes

MMP9
MMP3
MMP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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