Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline PDCDL1 Gene Variants Are Associated with Increased Primary Melanoma Thickness.

Biomolecules - 15 Apr 2025

Córdoba-Lanús Elizabeth, García-Pérez Omar, Melgar-Vilaplana Leticia, Domínguez-de-Barros Angélica, Fernández-de-Misa Ricardo

Abstract excerpt

Background: The incidence of malignant melanoma (MM) continues to increase annually, and tumour invasiveness is a main prognostic factor. Single-nucleotide polymorphisms (SNPs) have become key tools in the study of cancer genetics, influencing susceptibility and prognosis. Methods: In the present study, we analysed the relationship between five SNPs on the PDCDL1 gene (rs822336, rs822337, rs822338, rs229736,...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Apoptosis Regulatory Proteins
Share to Genetic Predisposition to Disease
Share to Genotype
Share to Melanoma
Share to Polymorphism, Single Nucleotide
Share to Prognosis
Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 40305358
DOI: 10.3390/biom15040584
PMCID: PMC12024702

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline PDCDL1 Gene Variants Are Associated with Increased Primary Melanoma Thickness.PMID 40305358Read ↗

Genome-Wide Methylation Profiles of Primary and Matched Distant Metastasis: Insights from the Dutch Early-Stage Melanoma (D-Esmel) StudySemantic proximity Read ↗

Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population.Semantic proximity Read ↗

Genome-wide association study identifies three new melanoma susceptibility loci.Semantic proximity Read ↗

Higher polygenic risk for melanoma is associated with improved survivalSemantic proximity Read ↗

PDCD1 gene polymorphisms as regulators of T-lymphocyte activity in cutaneous melanoma risk and prognosis.Semantic proximity Read ↗

Clinicopathological Study of a Series of Melanomas With IDH1 Mutation.Semantic proximity Read ↗

Association of XPD Gene Polymorphisms with Cutaneous Melanoma Risk: A Meta-Analysis and Trial Sequence Evaluation.Semantic proximity Read ↗

Germline and somatic mutations in patients with multiple primary melanomas: a next generation sequencing studySemantic proximity Read ↗

Germline variants in exonic regions have limited impact on immune checkpoint blockade clinical outcomes in advanced melanoma.Semantic proximity Read ↗

Association between PD-1 single nucleotide gene variants and the risk of metastatic melanoma.Semantic proximity Read ↗

Germline Variation in PDCD1 Is Associated with Overall Survival in Patients with Metastatic Melanoma Treated with Anti-PD-1 MonotherapySemantic proximity Read ↗

Germline variants are associated with increased primary melanoma tumor thickness at diagnosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.