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Article

Reverse guanine phosphoribosyltransferase selection of recombinant vaccinia viruses.

Virology - 1 Oct 1990

Isaacs S N, Kotwal G J, Moss B

Abstract excerpt

We have developed a procedure for the selection of recombinant vaccinia viruses with applicability to poxvirus mutagenesis studies and to the use of vaccinia virus as an expression vector. The method depends on the specific inability of a recombinant vaccinia virus expressing the Escherichia coli guanine phosphoriboxyltransferase gene (gpt) to form plaques on a hypoxanthine-guanine...

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Identifiers

PMID: 2219714
DOI: 10.1016/0042-6822(90)90367-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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