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Article

Species-specific features of DARC, the primate receptor for Plasmodium vivax and Plasmodium knowlesi.

Molecular biology and evolution - 1 Feb 2012

Demogines Ann, Truong Kimberly A, Sawyer Sara L

Abstract excerpt

The DARC (Duffy antigen/receptor for chemokines) gene, also called Duffy or FY, encodes a membrane-bound chemokine receptor. Two malaria parasites, Plasmodium vivax and Plasmodium knowlesi, use DARC to trigger internalization into red blood cells. Although much has been reported on the evolution of DARC null alleles, little is known about the evolution of the coding portion of this gene or the role that protein...

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Identifiers

PMID: 21878684
DOI: 10.1093/molbev/msr204
PMCID: PMC3258036

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Source receipt: pubmed, retrieved 7 Sept 2026.

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