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Article

Bone marrow-specific deficiency of nuclear receptor Nur77 enhances atherosclerosis.

Circulation research - 3 Feb 2012

Hamers Anouk A J, Vos Mariska, Rassam Fadi, Marinković Goran, Marincovic Goran, Kurakula Kondababu, van Gorp Patrick J, de Winther Menno P J, Gijbels Marion J J, de Waard Vivian, de Vries Carlie J M

Abstract excerpt

RATIONALE: Nuclear receptor Nur77, also known as NR4A1, TR3, or NGFI-B, is expressed in human atherosclerotic lesions in macrophages, endothelial cells, T cells and smooth muscle cells. Macrophages play a critical role in atherosclerosis and the function of Nur77 in lesion macrophages has not yet been investigated. OBJECTIVE: This study aims to delineate the function of Nur77 in macrophages and to assess the...

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Identifiers

PMID: 22194623
DOI: 10.1161/CIRCRESAHA.111.260760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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