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Resident Memory T Cells in the Atherosclerotic Lesion Associate With Reduced Macrophage Content and Increased Lesion Stability.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2024

de Jong Maaike J M, Depuydt Marie A C, Schaftenaar Frank H, Liu Kun, Maters David, Wezel Anouk, Smeets Harm J, Kuiper Johan, Bot Ilze, van Gisbergen Klaas, Slütter Bram

Abstract excerpt

BACKGROUND: Tissue resident memory T (TRM) cells are a T-cell subset that resides at the site of prior antigen recognition to protect the body against reoccurring encounters. Besides their protective function, TRM cells have also been implicated in inflammatory disorders. TRM cells are characterized by the expression of CD69 and transcription factors Hobit (homolog of Blimp-1 [B lymphocyte-induced maturation...

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PMID: 38634281
DOI: 10.1161/ATVBAHA.123.320511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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