Article
A single nucleotide polymorphism associates with the response of muscle ATP synthesis to long-term exercise training in relatives of type 2 diabetic humans.
Diabetes care - 1 Feb 2012
Kacerovsky-Bielesz Gertrud, Kacerovsky Michaela, Chmelik Marek, Farukuoye Michaela, Ling Charlotte, Pokan Rochus, Tschan Harald, Szendroedi Julia, Schmid Albrecht Ingo, Gruber Stephan, Herder Christian, Wolzt Michael, Moser Ewald, Pacini Giovanni, Smekal Gerhard, Groop Leif, Roden Michael
Abstract excerpt
OBJECTIVE: Myocellular ATP synthesis (fATP) associates with insulin sensitivity in first-degree relatives of subjects with type 2 diabetes. Short-term endurance training can modify their fATP and insulin sensitivity. This study examines the effects of moderate long-term exercise using endurance or resistance training in this cohort. RESEARCH DESIGN AND METHODS: A randomized, parallel-group trial tested 16...
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