Article
Potential role for interleukin-28B genotype in treatment decision-making in recent hepatitis C virus infection.
Hepatology (Baltimore, Md.) - 1 Oct 2010
Grebely Jason, Petoumenos Kathy, Hellard Margaret, Matthews Gail V, Suppiah Vijayaprakash, Applegate Tanya, Yeung Barbara, Marks Phillipa, Rawlinson William, Lloyd Andrew R, Booth David, Kaldor John M, George Jacob, Dore Gregory J
Abstract excerpt
UNLABELLED: Polymorphisms in the IL28B (interleukin-28B) gene region are important in predicting outcome following therapy for chronic hepatitis C virus (HCV) infection. We evaluated the role of IL28B in spontaneous and treatment-induced clearance following recent HCV infection. The Australian Trial in Acute Hepatitis C (ATAHC) was a study of the natural history and treatment of recent HCV, as defined by positive...
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