Article
Genetic variation in the interleukin-28B gene is not associated with fibrosis progression in patients with chronic hepatitis C and known date of infection.
Hepatology (Baltimore, Md.) - 1 Oct 2011
Marabita Francesco, Aghemo Alessio, De Nicola Stella, Rumi Maria G, Cheroni Cristina, Scavelli Rossana, Crimi Marco, Soffredini Roberta, Abrignani Sergio, De Francesco Raffaele, Colombo Massimo
Abstract excerpt
UNLABELLED: Polymorphisms in the interleukin-28B (IL28B) region are associated with spontaneous and treatment-induced viral clearance in hepatitis C virus (HCV) infection. Nevertheless, it is unknown whether genetic variation at the IL28B locus influences the natural history of chronic HCV infection. Thus, we asked whether an association between IL28B polymorphisms and liver fibrosis progression existed. We...
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