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Article

Genotype B of Killer Cell Immunoglobulin-Like Receptor is Related with Gastric Cancer Lesions.

Scientific reports - 17 Apr 2018

Hernandez Eric G, Partida-Rodriguez Oswaldo, Camorlinga-Ponce Margarita, Nieves-Ramirez Miriam, Ramos-Vega Irma, Torres Javier, Perez-Rodriguez Martha

Abstract excerpt

NK cells are important in innate immunity for their capacity to kill infected or cancer cells. The killer cell immunoglobulin-like receptors (KIR) are a family of polymorphic genes with inhibitory and activating functions. The main driving force for gastric cancer (GC) development is a chronic response, which causes an increase of NK cells in the gastric mucosa. The aim of this work was to study polymorphisms in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29666399
DOI: 10.1038/s41598-018-24464-2
PMCID: PMC5904182

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