Article
Association of CYP2C19*3 gene polymorphism with breast cancer in Chinese women.
Genetics and molecular research : GMR - 5 Dec 2011
Gan C Q, Wang X Y, Cao Y D, Ye W X, Liu H, Sun Y Y
Abstract excerpt
Cytochrome P450 (CYP) 2C19 metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids, which significantly promote proliferation of cancer cells in vitro and in vivo. We looked for a possible association between human CYP2C19*3 gene polymorphism and breast cancer in the Chinese Han population. In a Chinese Han case-control study of breast cancer patients (N = 600) and age- and...
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