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Article

A critical reassessment of the role of mitochondria in tumorigenesis.

PLoS medicine - 1 Nov 2005

Salas Antonio, Yao Yong-Gang, Macaulay Vincent, Vega Ana, Carracedo Angel, Bandelt Hans-Jürgen

Abstract excerpt

BACKGROUND: Mitochondrial DNA (mtDNA) is being analyzed by an increasing number of laboratories in order to investigate its potential role as an active marker of tumorigenesis in various types of cancer. Here we question the conclusions drawn in most of these investigations, especially those published in high-rank cancer research journals, under the evidence that a significant number of these medical mtDNA...

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Identifiers

PMID: 16187796
DOI: 10.1371/journal.pmed.0020296
PMCID: PMC1240051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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