Article
APE1 Asp148Glu polymorphism and lung cancer susceptibility.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2014
Cai Liyun, Fu Yingjv, Zhang Yuanyue
Abstract excerpt
Apurinic/apyrimidinic endonuclease 1 (APE1) is a key enzyme in base excision repair (BER) pathway for the removal of many oxidized and alkylated bases. Single-nucleotide polymorphisms of the APE1gene have been demonstrated to be involved in carcinogenesis. However, the association between APE1 Asp148Glu polymorphism and lung cancer risk remains inconclusive. To derive a precise estimate for this association, we...
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