Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lymphoblastoid Cell Lines in Pharmacogenomic Discovery and Clinical Translation

19 Dec 2011

Abstract excerpt

The ability to predict how an individual patient will respond to a particular treatment is the ambitious goal of personalized medicine. The genetic make up of an individual has been shown to play a role in drug response. For pharmacogenomic studies, human lymphoblastoid cell lines (LCLs) comprise a useful model system for identifying genetic variants associated with pharmacologic phenotypes. The availability of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Genetic Associations and Epidemiology
Share to Pharmacogenetics and Drug Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22176622
DOI: 10.2217/pgs.11.121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lymphoblastoid Cell Lines in Pharmacogenomic Discovery and Clinical TranslationPMID 22176622Read ↗

Lymphoblastoid cell lines models of drug response: successes and lessons from this pharmacogenomic model.Semantic proximity Read ↗

Use of CEPH and non-CEPH lymphoblast cell lines in pharmacogenetic studies.Semantic proximity Read ↗

Use of cell lines in the investigation of pharmacogenetic loci.Semantic proximity Read ↗

Clinical translation of cell-based pharmacogenomic discovery.Semantic proximity Read ↗

Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines.Semantic proximity Read ↗

In vitro human cell line models to predict clinical response to anticancer drugs.Semantic proximity Read ↗

Identifying genetic modulators of statin response using subject-derived lymphoblastoid cell lines.Semantic proximity Read ↗

Human lymphoblastoid cell lines: a goldmine for the biobankomics era.Semantic proximity Read ↗

Genome-wide association and pharmacological profiling of 29 anticancer agents using lymphoblastoid cell lines.Semantic proximity Read ↗

Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.Semantic proximity Read ↗

Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines.Semantic proximity Read ↗

Impact of the 1000 genomes project on the next wave of pharmacogenomic discovery.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.