Article
Use of CEPH and non-CEPH lymphoblast cell lines in pharmacogenetic studies.
Pharmacogenomics - 1 Apr 2005
Shukla Sunita J, Dolan M Eileen
Abstract excerpt
A long-term goal of pharmacogenomic research is the design of individualized therapy based on the genomic sequence of the patient in order to maximize response and minimize adverse drug reactions. Identifying genetic variants that predict drug response is challenging because drug responses reflect not only properties intrinsic to the target cell, but also host metabolic factors. One model that is currently being...
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