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Article

Lectin complement pathway gene profile of donor and recipient determine the risk of bacterial infections after orthotopic liver transplantation.

Hepatology (Baltimore, Md.) - 1 Sept 2010

de Rooij Bert-Jan F, van Hoek Bart, ten Hove W Rogier, Roos Anja, Bouwman Lee H, Schaapherder Alexander F, Porte Robert J, Daha Mohamed R, van der Reijden Johan J, Coenraad Minneke J, Ringers Jan, Baranski Andrzej G, Hepkema Bouke G, Hommes Daniel W, Verspaget Hein W

Abstract excerpt

UNLABELLED: Infectious complications after orthotopic liver transplantation (OLT) are a major clinical problem. The lectin pathway of complement activation is liver-derived and a crucial effector of the innate immune defense against pathogens. Polymorphisms in lectin pathway genes determine their functional activity. We assessed the relationship between these polymorphic genes and clinically significant bacterial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20593422
DOI: 10.1002/hep.23782

Genes

FCN2
MASP2
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lectin complement pathway gene profile of donor and recipient determine the risk of bacterial infections after orthotopic liver transplantation.PMID 20593422Read ↗

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