Article
Translation of the Saccharomyces cerevisiae tcm1 gene in the absence of a 5'-untranslated leader.
Nucleic acids research - 11 Oct 1990
Maicas E, Shago M, Friesen J D
Abstract excerpt
The role of eukaryotic 5'-untranslated messenger RNA leaders is not entirely clear, since they share little sequence similarity among each other. The importance of the leader in determining the efficiency of translation initiation was addressed here by examining the polyribosome distribution of several leader-deletion alleles of the yeast tcm1 gene (coding for ribosomal protein L3). Shortening of this...
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