Article
A point mutation in the 5'-untranslated leader that affects translational activation of the mitochondrial COX3 mRNA.
Current genetics - 1 Jun 1995
Costanzo M C, Fox T D
Abstract excerpt
The 613-base 5'-untranslated leader (5'-UTL) of the Saccharomyces cerevisiae mitochondrial COX3 mRNA contains the target of an mRNA-specific translational activator complex composed of at least three nuclearly encoded proteins. We have genetically mapped a collection of cox3 point mutations, using a set of defined COX3 deletions, and found one to be located in the region coding the 5'-UTL. The strain carrying...
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