Article
Profiling retinal biochemistry in the MPDZ mutant retinal dysplasia and degeneration chick: a model of human RP and LCA.
Investigative ophthalmology & visual science - 25 Jan 2012
Beattie James R, Finnegan Sorcha, Hamilton Ross W, Ali Manir, Inglehearn Christopher F, Stitt Alan W, McGarvey John J, Hocking Paul M, Curry William J
Abstract excerpt
PURPOSE: Raman microscopy, a rapid nondestructive technique that profiles the composition of biological samples, was used to characterize retinal biochemistry in the retinal dysplasia and degeneration (rdd) and wild-type (wt) chick retina during retinogenesis and at hatching. METHODS: Embryonic day (E)13 and posthatch day (P)1 rdd and wt retinal cross-sections (n = 3 of each line at each age) were profiled using...
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