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Article

The retina/RPE proteome in chick myopia and hyperopia models: Commonalities with inherited and age-related ocular pathologies.

Molecular vision - 1 Jan 2017

Riddell Nina, Faou Pierre, Murphy Melanie, Giummarra Loretta, Downs Rachael A, Rajapaksha Harinda, Crewther Sheila G

Abstract excerpt

Purpose: Microarray and RNA sequencing studies in the chick model of early optically induced refractive error have implicated thousands of genes, many of which have also been linked to ocular pathologies in humans, including age-related macular degeneration (AMD), choroidal neovascularization, glaucoma, and cataract. These findings highlight the potential relevance of the chick model to understanding both...

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Source

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Identifiers

PMID: 29259393
PMCID: PMC5723150

Genes

RPE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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