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Article

Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer

8 Dec 2011

Abstract excerpt

Progression of primary prostate cancer to castration-resistant prostate cancer (CRPC) is associated with numerous genetic and epigenetic alterations that are thought to promote survival at metastatic sites. In this study, we investigated gene copy number and CpG methylation status in CRPC to gain insight into specific pathophysiologic pathways that are active in this advanced form of prostate cancer. Our analysis...

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Share to Epigenetics and DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 22158653
DOI: 10.1158/0008-5472.can-11-2079

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