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The molecular underpinnings of prostate cancer: impacts on management and pathology practice

18 Oct 2016

Abstract excerpt

Prostate cancer (PCa) is a clinically heterogeneous disease and current treatment strategies are based largely on anatomical and pathological parameters. In the recent past, several DNA sequencing studies of primary and advanced PCa have revealed recurrent patterns of genomic aberrations that expose mechanisms of resistance to available therapies and potential new drug targets. Suppression of androgen receptor...

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PMID: 27753448
DOI: 10.1002/path.4826

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