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Article

Genomic Alteration Burden in Advanced Prostate Cancer and Therapeutic Implications

22 Nov 2019

Abstract excerpt

The increasing number of patients with sequenced prostate cancer genomes enables us to study not only individual oncogenic mutations, but also capture the global burden of genomic alterations. Here we review the extent of tumor genome mutations and chromosomal structural variants in various clinical states of prostate cancer, and the related prognostic information. Next, we discuss the underlying mutational...

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Identifiers

PMID: 31824860
DOI: 10.3389/fonc.2019.01287

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