Article
Epigenomic alterations in localized and advanced prostate cancer.
Neoplasia (New York, N.Y.) - 1 Apr 2013
Lin Pei-Chun, Giannopoulou Eugenia G, Park Kyung, Mosquera Juan Miguel, Sboner Andrea, Tewari Ashutosh K, Garraway Levi A, Beltran Himisha, Rubin Mark A, Elemento Olivier
Abstract excerpt
Although prostate cancer (PCa) is the second leading cause of cancer death among men worldwide, not all men diagnosed with PCa will die from the disease. A critical challenge, therefore, is to distinguish indolent PCa from more advanced forms to guide appropriate treatment decisions. We used Enhanced Reduced Representation Bisulfite Sequencing, a genome-wide high-coverage single-base resolution DNA methylation...
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