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Article

Association of the GGCX (CAA)16/17 repeat polymorphism with higher warfarin dose requirements in African Americans.

Pharmacogenetics and genomics - 1 Feb 2012

Cavallari Larisa H, Perera Minoli, Wadelius Mia, Deloukas Panos, Taube Gelson, Patel Shitalben R, Aquino-Michaels Keston, Viana Marlos A G, Shapiro Nancy L, Nutescu Edith A

Abstract excerpt

OBJECTIVE: Little is known about genetic contributors to higher than usual warfarin dose requirements, particularly for African Americans. This study tested the hypothesis that the γ-glutamyl carboxylase (GGCX) genotype contributes to warfarin dose requirements greater than 7.5 mg/day in an Afric...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22158446
DOI: 10.1097/FPC.0b013e32834f288f
PMCID: PMC3261355

Genes

GGCX
VKORC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22158446-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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