New genetic variant that might improve warfarin dose prediction in African Americans.

doi:10.1111/j.1365-2125.2010.03709.x

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Article

New genetic variant that might improve warfarin dose prediction in African Americans.

British journal of clinical pharmacology - 1 Sept 2010

Schelleman Hedi, Brensinger Colleen M, Chen Jinbo, Finkelman Brian S, Rieder Mark J, Kimmel Stephen E

Abstract excerpt

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: Variants in the CYP2C9 (i.e. *2 and *3) and VKORC1 (i.e. 1173C/T or -1639G/A) genes have been shown to influence warfarin dose requirements. However, these factors seem to explain less of the dose variability in African Americans who have a lower prevalence of the CYP2C9*2 and *3 and VKORC1 1173T alleles. WHAT THIS STUDY ADDS: In African Americans, the VKORC1 rs17886199...

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Identifiers

PMID: 20716240
DOI: 10.1111/j.1365-2125.2010.03709.x
PMCID: PMC2949912

Genes

VKORC1
EPHX1
ALB
GGCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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