Article
Association of genetic polymorphisms with warfarin dose requirements in Chinese patients.
Genetic testing and molecular biomarkers - 1 Dec 2013
Liang Yundan, Chen Zhiyu, Guo Gang, Dong Xuemei, Wu Chunting, Li He, Wang Tong, Xu Bingying
Abstract excerpt
OBJECTIVE: Warfarin is a commonly used anticoagulant with a narrow therapeutic range and large interindividual differences in dosing requirements. Previously, studies have identified that the interindividual variability was influenced by varieties of factors, including age, body size, vitamin K intake, interacting medications, as well as genetic variants. We aimed to investigate the effect of single-nucleotide...
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