Article
Effects of rare CYP2C9 alleles on stable warfarin doses in Chinese Han patients with atrial fibrillation.
Pharmacogenomics - 1 Sept 2020
Wang Dongxu, Dai Da-Peng, Wu Hualan, Chong Jia, Lü You, Yin Ruoyun, Zhao Xinlong, Zhao Anxu, Yang Jiefu, Chen Hao
Abstract excerpt
Aim: Gene polymorphisms are critical in warfarin dosing variation. Here, the role of rare CYP2C9 alleles on warfarin doses in Chinese Han patients was investigated. Methods: A retrospective study recruited 681 warfarin treated atrial fibrillation patients. The genetic and clinical data were collected. Dose-related variables were selected by univariate analyses and the warfarin-dosing algorithm was derived by...
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