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Article

Microglia express distinct M1 and M2 phenotypic markers in the postnatal and adult central nervous system in male and female mice.

Journal of neuroscience research - 1 Sept 2013

Crain Jessica M, Nikodemova Maria, Watters Jyoti J

Abstract excerpt

Although microglial activation is associated with all CNS disorders, many of which are sexually dimorphic or age-dependent, little is known about whether microglial basal gene expression is altered with age in the healthy CNS or whether it is sex dependent. Analysis of microglia from the brains of 3-day (P3)- to 12-month-old male and female C57Bl/6 mice revealed distinct gene expression profiles during postnatal...

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PMID: 23686747
DOI: 10.1002/jnr.23242
PMCID: PMC3715560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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