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Article

Ikaros gene expression and leukemia.

Leukemia & lymphoma - 1 Jan 2002

Tonnelle Cécile, Calmels Boris, Maroc Christine, Gabert Jean, Chabannon Christian

Abstract excerpt

The Ikaros (Ik) protein, or LyF1, was initially described as a protein binding to regulatory sequences of a number of genes expressed in murine lymphoid cells. Ikaros is a critical regulator of normal hematopoietic stem cell differentiation, as evidenced by dramatic defects in the lymphoid compartments, in homozygous animals with gene inactivation. Because differential splicing produces multiple isoforms with...

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Identifiers

PMID: 11908734
DOI: 10.1080/10428190210186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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