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Article

Quantitative trait Loci association mapping by imputation of strain origins in multifounder crosses.

Genetics - 1 Feb 2012

Zhou Jin J, Ghazalpour Anatole, Sobel Eric M, Sinsheimer Janet S, Lange Kenneth

Abstract excerpt

Although mapping quantitative traits in inbred strains is simpler than mapping the analogous traits in humans, classical inbred crosses suffer from reduced genetic diversity compared to experimental designs involving outbred animal populations. Multiple crosses, for example the Complex Trait Consortium's eight-way cross, circumvent these difficulties. However, complex mating schemes and systematic inbreeding...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22143921
DOI: 10.1534/genetics.111.135095
PMCID: PMC3276647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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