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Article

QTL mapping in outbred populations: successes and challenges.

Physiological genomics - 1 Feb 2014

Solberg Woods Leah C

Abstract excerpt

Quantitative trait locus (QTL) mapping in animal populations has been a successful strategy for identifying genomic regions that play a role in complex diseases and traits. When conducted in an F2 intercross or backcross population, the resulting QTL is frequently large, often encompassing 30 Mb or more and containing hundreds of genes. To narrow the locus and identify candidate genes, additional strategies are...

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Share to Animals, Congenic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24326347
DOI: 10.1152/physiolgenomics.00127.2013
PMCID: PMC4073892

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