PER2 rs2304672 polymorphism moderates circadian-relevant reward circuitry activity in adolescents.

doi:10.1016/j.biopsych.2011.10.012

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Article

PER2 rs2304672 polymorphism moderates circadian-relevant reward circuitry activity in adolescents.

Biological psychiatry - 1 Mar 2012

Forbes Erika E, Dahl Ronald E, Almeida Jorge R C, Ferrell Robert E, Nimgaonkar Vishwajit L, Mansour Hader, Sciarrillo Samantha R, Holm Stephanie M, Rodriguez Eric E, Phillips Mary L

Abstract excerpt

BACKGROUND: Reward behavior in animals is influenced by circadian genes, including clock-pathway genes such as Period2 (PER2). Several forms of psychiatric illness are associated with both altered reward function and disturbances in circadian function. The PER2 single nucleotide polymorphism (SNP) rs2304672 has been associated with psychiatric illnesses involving reward dysfunction. Associations among circadian...

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Identifiers

PMID: 22137505
DOI: 10.1016/j.biopsych.2011.10.012
PMCID: PMC3323120

Genes

PER2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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