Article
A Three-Way Interaction of Sex, PER2 rs56013859 Polymorphism, and Family Maltreatment in Depressive Symptoms in Adolescents.
Genes - 29 Aug 2023
Torres Soler Catalina, Kanders Sofia H, Rehn Mattias, Olofsdotter Susanne, Åslund Cecilia, Nilsson Kent W
Abstract excerpt
The prevalence of depressive symptoms in adolescents is 12-18% and is twice as frequent in females. Sleep problems and thoughts of death are depressive symptoms or co-occurrent phenomena. Family maltreatment is a risk factor for later depressive symptoms and the period circadian regulator (PER) has been studied in relation to neurotransmitters, adaptation to stress, and winter depression. The purpose of this work...
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