Article

Machine Learning and In-Vivo Expression Analyses Reveal Circadian Clock Features Predictive of Anxiety in Humans

2021-12-29

Abstract excerpt

Mood disorders, including anxiety, are associated with disruptions in circadian rhythms and are linked to polymorphisms in circadian clock genes. Molecular mechanisms underlying these connections may be direct—via transcriptional activity of clock genes on downstream mood pathways in the brain, or indirect—via clock gene influences on the phase and amplitude of circadian rhythms which, in turn, modulate physiologi...

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Literature Corpus work: 75a56415-cd86-51ac-bbf2-6500f9796bd9
DOI: 10.21203/rs.3.rs-1190238/v1

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