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Article

Molecular Mechanisms of Injury in HIV-Associated Nephropathy

7 Jun 2018

Abstract excerpt

HIV-associated nephropathy (HIVAN) is an important cause of secondary focal glomerulosclerosis that occurs primarily in persons of African ancestry with advanced HIV disease. Although HIVAN is characterized by severe proteinuria and rapid progression to end stage renal disease without treatment, the phenotype is markedly attenuated by treatment with antiretroviral medications. HIV infection of glomerular and...

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PMID: 29930940
DOI: 10.3389/fmed.2018.00177

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