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Article

Associations of polymorphisms of folate cycle enzymes and risk of breast cancer in a Brazilian population are age dependent.

Molecular biology reports - 1 Apr 2012

Carvalho Barbosa Rita de Cássia, Menezes Débora Costa, Freire Thiago Fernando Vasconcelos, Sales Diogo Campos, Alencar Victor Hugo Medeiros, Rabenhorst Silvia Helena Barem

Abstract excerpt

Polymorphisms in genes involved in folate metabolism have been shown to be implicated in breast cancer risk but with contradictory results. In this case-control study, we investigated the association between MTHFR C677T and A1298C, TYMS 5'-UTR, MTR A2756G and cSHMT C1420T and also the folate carrier (RFC1 G80A) and breast cancer risk in a northeastern Brazilian population. The study included 183 women diagnosed...

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Source

Identifiers

PMID: 22134752
DOI: 10.1007/s11033-011-1285-1

Genes

MTR
RFC1
MTHFR
TYMS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Associations of polymorphisms of folate cycle enzymes and risk of breast cancer in a Brazilian population are age dependent.PMID 22134752Read ↗

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