Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of MTHFR C677T and A1298C, and MTR A2756G gene polymorphisms in breast cancer risk in a population in Northeast Brazil.

Anticancer research - 1 Nov 2012

de Cássia Carvalho Barbosa Rita, da Costa Débora Menezes, Cordeiro Denise Ellen Francelino, Vieira Ana Patricia Freitas, Rabenhorst Silvia Helena Barem

Abstract excerpt

Polymorphisms in genes encoding enzymes of folate metabolism are a focus of breast cancer risk studies due of the role of these enzymes in DNA methylation, synthesis, and repair. MTHFR, encoding for 5,10-methylenetetrahydrofolate reductase, is one of the most studied genes in this regard, but findings are controversial, and the majority of studies have analyzed polymorphisms individually. In this case control...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Age Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Brazil

Share to Breast Neoplasms

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Restriction Fragment Length

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to Risk Factors

Source

Identifiers

PMID: 23155246

Genes

MTHFR
MTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of MTHFR C677T and A1298C, and MTR A2756G gene polymorphisms in breast cancer risk in a population in Northeast Brazil.PMID 23155246Read ↗

The methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Asian populations.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk: a meta-analysis from 41 studies with 16,480 cases and 22,388 controls.Semantic proximity Read ↗

Associations of polymorphisms of folate cycle enzymes and risk of breast cancer in a Brazilian population are age dependent.Semantic proximity Read ↗

Increased breast cancer risk at high plasma folate concentrations among women with the MTHFR 677T allele.Semantic proximity Read ↗

Association between the MTHFR C677T Polymorphism and Breast Cancer Risk: A Meta-Analysis of 23 Case-Control Studies.Semantic proximity Read ↗

Association of the MTHFR Gene C677T Polymorphism with Breast Cancer in a Turkish Population.Semantic proximity Read ↗

Role of polymorphism of methyltetrahydrofolate-homocysteine methyltransferase (MTR) A2756G and breast cancer risk.Semantic proximity Read ↗

MTHFR polymorphisms, dietary folate intake, and breast cancer risk: results from the Shanghai Breast Cancer Study.Semantic proximity Read ↗

A meta-analysis of genotypes and haplotypes of methylenetetrahydrofolate reductase gene polymorphisms in breast cancer.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Moroccan women.Semantic proximity Read ↗

MTHFR C677T and A1298C Polymorphisms in Breast Cancer, Gliomas and Gastric Cancer: A Review.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms in breast cancer: a Sardinian preliminary case-control studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.