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Article

Controversial roles of methylenetetrahydrofolate reductase polymorphisms and folate in breast cancer disease.

International journal of food sciences and nutrition - 1 Feb 2015

Bravatà Valentina

Abstract excerpt

Breast cancer (BC) represents a highly heterogeneous tumour at both the clinical and molecular levels. Single-nucleotide polymorphisms (SNPs) of the folate-metabolising enzyme methylenetetrahydrofolate-reductase (MTHFR) may modify the association between folate intake and BC and influence plasma folate concentration. The role of folate in BC is equivocal, association studies between the common MTHFR SNPs C677T...

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Source

Identifiers

PMID: 25318348
DOI: 10.3109/09637486.2014.959896

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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