Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the folate-metabolizing genes MTR, MTRR, and CBS and breast cancer risk.

Cancer epidemiology - 1 Apr 2012

Weiner Alexandra S, Boyarskikh Uljana A, Voronina Elena N, Selezneva Inna A, Sinkina Tatiana V, Lazarev Alexandr F, Petrova Valentina D, Filipenko Maxim L

Abstract excerpt

Alterations in the nucleotide sequences of folate-metabolizing genes can increase the risk of malignant transformation. The aim of our study was to investigate the association of three single-nucleotide polymorphisms (SNPs) in the folate-metabolizing genes - A2756G MTR, A66G MTRR, and 844ins68 CBS - which have putative functional significance in breast cancer risk. The allele and genotype frequencies of the SNPs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystathionine beta-Synthase

Share to Ferredoxin-NADP Reductase

Share to Folic Acid

Share to Polymorphism, Restriction Fragment Length

Share to Real-Time Polymerase Chain Reaction

Share to Risk Factors

Source

Identifiers

PMID: 22236648
DOI: 10.1016/j.canep.2011.11.010

Genes

CBS
MTR
MTRR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the folate-metabolizing genes MTR, MTRR, and CBS and breast cancer risk.PMID 22236648Read ↗

MTRR A66G polymorphism and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Polymorphisms in folate-metabolizing genes and risk of non-Hodgkin's lymphoma.Semantic proximity Read ↗

Role of polymorphism of methyltetrahydrofolate-homocysteine methyltransferase (MTR) A2756G and breast cancer risk.Semantic proximity Read ↗

MTHFR C677T and A1298C Polymorphisms in Breast Cancer, Gliomas and Gastric Cancer: A Review.Semantic proximity Read ↗

Controversial roles of methylenetetrahydrofolate reductase polymorphisms and folate in breast cancer disease.Semantic proximity Read ↗

Polymorphisms in the MTHFR gene are associated with breast cancer.Semantic proximity Read ↗

MTRR polymorphism and the risk for colorectal and breast cancer in Romanian patients--a preliminary study.Semantic proximity Read ↗

Polymorphisms in folate metabolizing enzymes and transport proteins and the risk of breast cancer.Semantic proximity Read ↗

Interaction of MTHFR C677T and A1298C, and MTR A2756G gene polymorphisms in breast cancer risk in a population in Northeast Brazil.Semantic proximity Read ↗

Association between 11 genetic polymorphisms in folate-metabolising genes and head and neck cancer risk.Semantic proximity Read ↗

Association of folate metabolism-related genetic polymorphisms with susceptibility to breast cancer: A protocol for a systematic review and meta-analysis.Semantic proximity Read ↗

Association of Intake Folate and Related Gene Polymorphisms with Breast Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.