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Article

Homozygosity at the C677T of the MTHFR gene is associated with increased breast cancer risk in the Turkish population.

In vivo (Athens, Greece) - 1 Jan 2000

Deligezer Ugur, Akisik E Ebru, Dalay Nejat

Abstract excerpt

BACKGROUND: Folate deficiency is implicated in cancer development. Single nucleotide polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene can modulate the effect of folate. In this case-controlled study, a possible effect of the common MTHFR C677T (ala-->val) polymorphism on breast cancer susceptibility in Turkish patients was investigated. MATERIALS AND METHODS: Polymorphism analysis was...

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Identifiers

PMID: 16097444

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Homozygosity at the C677T of the MTHFR gene is associated with increased breast cancer risk in the Turkish population.PMID 16097444Read ↗

Association of the MTHFR Gene C677T Polymorphism with Breast Cancer in a Turkish Population.Semantic proximity Read ↗

The methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Asian populations.Semantic proximity Read ↗

MTHFR polymorphisms and breast cancer riskSemantic proximity Read ↗

Association between the MTHFR C677T Polymorphism and Breast Cancer Risk: A Meta-Analysis of 23 Case-Control Studies.Semantic proximity Read ↗

MTHFR C677T polymorphism associated with breast cancer susceptibility: a meta-analysis involving 15,260 cases and 20,411 controls.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphism and susceptibility to breast cancer.Semantic proximity Read ↗

A meta-analysis of genotypes and haplotypes of methylenetetrahydrofolate reductase gene polymorphisms in breast cancer.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk: a meta-analysis from 41 studies with 16,480 cases and 22,388 controls.Semantic proximity Read ↗

[Association between genetic polymorphisms in methylenetetrahydrofolate reductase and risk of breast cancer].Semantic proximity Read ↗

No association between methylenetetrahydrofolate reductase C677T polymorphism and breast cancer.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Moroccan women.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene C677T polymorphism and breast cancer risk: Evidence for genetic susceptibilitySemantic proximity Read ↗

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