Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The polymorphisms of T cell-specific TBX21 and STAT4 genes may contribute to the susceptibility of Chinese individuals to aplastic anemia.

Human immunology - 1 Jan 2012

Ge Meili, Zheng Yizhou, Li Xingxin, Shi Jun, Ge Jing, Li Huiyuan, Feng Sizhou

Abstract excerpt

T cell-specific T-box transcription factor gene (TBX21) and signal transducer and activator of transcription 4 (STAT4) have been suggested as 2 candidate genes for conferring susceptibility to autoimmunity. We herein hypothesized that the polymorphisms of TBX21 and STAT4 genes might contribute to the susceptibility of Chinese individuals to aplastic anemia (AA) as T cell-mediated immune disease characterized by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Aplastic
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to STAT4 Transcription Factor

Share to T-bet Transcription Factor

Share to T-Box Domain Proteins

Share to T-Lymphocytes

Share to Young Adult

Source

Identifiers

PMID: 22133489
DOI: 10.1016/j.humimm.2011.11.007

Genes

STAT4
TBX21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The polymorphisms of T cell-specific TBX21 and STAT4 genes may contribute to the susceptibility of Chinese individuals to aplastic anemia.PMID 22133489Read ↗

The polymorphisms of T cell-specific TBX21 gene may contribute to the susceptibility of chronic immune thrombocytopenia in Chinese population.Semantic proximity Read ↗

Association of TBX21 gene haplotypes in a Chinese population with systemic lupus erythematosus.Semantic proximity Read ↗

Association of TBX21 promoter polymorphisms with type 1 autoimmune hepatitis in a Chinese population.Semantic proximity Read ↗

Association of aplastic anemia and FoxP3 gene polymorphisms in Koreans.Semantic proximity Read ↗

Influence of genetic polymorphisms of IL23R, STAT3, IL12B, and STAT4 on the risk of aplastic anemia and the effect of immunosuppressive therapy.Semantic proximity Read ↗

Polymorphisms of the TGF-β1 gene and the risk of acquired aplastic anemia in a Chinese population.Semantic proximity Read ↗

Association of HLA class II (-DRB1,-DQB1,-DPB1) alleles and haplotypes on susceptibility to aplastic anemia in northern Chinese Han.Semantic proximity Read ↗

Current Concepts of the Pathogenesis of Aplastic AnemiaSemantic proximity Read ↗

Influence of TBX21 T-1993C variant on autoimmune hepatitis development by Yin-Yang 1 binding.Semantic proximity Read ↗

TRAF1/C5 rs10818488 polymorphism is not a genetic risk factor for acquired aplastic anemia in a Chinese population.Semantic proximity Read ↗

Association of the rs17250932, rs4794067, and rs2240017 polymorphism in the TBX21 gene with autoimmune diseases: A meta-analysis.Semantic proximity Read ↗

Implementation of NUDT15 Genotyping to Prevent Azathioprine-Induced Leukopenia for Patients With Autoimmune Disorders in Chinese Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.