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Article

Association of aplastic anemia and FoxP3 gene polymorphisms in Koreans.

Hematology (Amsterdam, Netherlands) - 1 Apr 2017

In Ji Won, Lee Nuri, Roh Eun Youn, Shin Sue, Park Kyoung Un, Song Eun Young

Abstract excerpt

OBJECTIVES: Aplastic anemia (AA) is characterized by pancytopenia and bone marrow failure, and most acquired AA is an immune-mediated disorder. Regulatory T cells (Tregs) suppressing autoreactive T cells were decreased in AA patients. FoxP3 is a major regulator for the development and function of Tregs. Polymorphism in FoxP3 was shown to be associated with various autoimmune diseases, however, has not yet been...

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Identifiers

PMID: 27702400
DOI: 10.1080/10245332.2016.1238645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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