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Article

Influence of TBX21 T-1993C variant on autoimmune hepatitis development by Yin-Yang 1 binding.

World journal of gastroenterology - 28 Dec 2017

Sun Wei, Wu Hong-Yan, Chen Song

Abstract excerpt

AIM: To investigated the mechanism of the association between the TBX21 T-1993C promoter polymorphism and autoimmune hepatitis type 1 (AIH-1) development. METHODS: In vivo, In vivo, and reporter analyses were performed to determine the function of transcription factors binding to the T-1993C element of the TBX21 promoter in human CD4+ T and B cell lines. Flow cytometry and quantitative real-time PCR were used to...

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Source

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Identifiers

PMID: 29358858
DOI: 10.3748/wjg.v23.i48.8500
PMCID: PMC5752710

Genes

TBX21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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