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Article

Genetic polymorphisms in metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine.

Journal of applied toxicology : JAT - 1 Jan 2013

Kim Dojung, Lee Young-Joo, Ryu Heui-Young, Lee Jin-Hee, Kim Hyun-Kyung, Kim Eunhee, Moon Jae-Dong, Chang Dong Deuk, Yoon Hae-Seong

Abstract excerpt

Heterocyclic amines (HCAs) are naturally produced during common cooking processes for meats and fish. HCAs are metabolized by various enzymes, including cytochromes P450, N-acetyl transferases, and sulfotransferases, and their bioactivated metabolites are considered to bind to DNA or protein to show carcinogenic effects. More than 20 HCAs have been identified, of which...

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PMID: 22131055
DOI: 10.1002/jat.1712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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