Article
Identification of genetic variants of the IL-22 gene in association with an altered risk of COPD susceptibility.
The clinical respiratory journal - 1 Aug 2022
Wang Yan, Zhou Qipeng, Chen Lingzhu, Dong Lian, Xiong Mingmei, Xie Xiaohui, Zhao Li, Xu Jingyi, Zheng Zeguang, Wang Jian, Lu Wenju
Abstract excerpt
The incidence of chronic obstructive pulmonary disease (COPD) is related to the interaction between environmental exposure and genetic factors. Far more than 15% of smokers eventually develop COPD. In addition to smoking, genetic susceptibility may be another factor in the development of COPD. IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis. Here, we conducted a...
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