Article
An SNP selection strategy identified IL-22 associating with susceptibility to tuberculosis in Chinese.
Scientific reports - 1 Jan 2011
Zhang Guoliang, Chen Xinchun, Chan Long, Zhang Mingxia, Zhu Baohua, Wang Lantian, Zhu Xiuyun, Zhang Jieyun, Zhou Boping, Wang Junwen
Abstract excerpt
Recent studies showed that IL-22 plays a protective role in the host defense. However, the contribution of polymorphisms of the IL-22 gene to human TB susceptibility remains untested. We have designed a computational approach to select functional SNPs in the IL-22 gene and genotyped them in a two...
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