Article
Higher circulating levels of chemokine CCL22 in patients with breast cancer: evaluation of the influences of tumor stage and chemokine gene polymorphism.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2015
Jafarzadeh A, Fooladseresht H, Minaee K, Bazrafshani M R, Khosravimashizi A, Nemati M, Mohammadizadeh M, Mohammadi M M, Ghaderi A
Abstract excerpt
The receptor for CCL22 is named CCR4 that preferentially is expressed on the regulatory T cells (Treg), and accordingly, CCL22 acts as a chemoattractant for the intratumoral Treg migration. The aim of this study was to evaluate the serum CCL22 levels and a single nucleotide polymorphism (SNP) in chemokine gene, [2030 G/C (rs223818)], in patients with breast cancer. Blood samples were collected from 100 women with...
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