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Article

Evidence-based annotation of gene function in Shewanella oneidensis MR-1 using genome-wide fitness profiling across 121 conditions.

PLoS genetics - 1 Nov 2011

Deutschbauer Adam, Price Morgan N, Wetmore Kelly M, Shao Wenjun, Baumohl Jason K, Xu Zhuchen, Nguyen Michelle, Tamse Raquel, Davis Ronald W, Arkin Adam P

Abstract excerpt

Most genes in bacteria are experimentally uncharacterized and cannot be annotated with a specific function. Given the great diversity of bacteria and the ease of genome sequencing, high-throughput approaches to identify gene function experimentally are needed. Here, we use pools of tagged transposon mutants in the metal-reducing bacterium Shewanella oneidensis MR-1 to probe the mutant fitness of 3,355 genes in...

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Identifiers

PMID: 22125499
DOI: 10.1371/journal.pgen.1002385
PMCID: PMC3219624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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